Annona muricata L.

Annonaceae

Common Names:
Katu-anoda, Katu-attha (S)
Mul-annamunna (T)
Prickly custard apple, Soursop (E)
Sitaphal (Sa)

Traditional Knowledge

Useful plant parts :
Fruit, young leaf and flower

Uses in traditional medicine :

Fruit is edible and used as a remedy for cancers, urinary diseases, to dissolve kidney stones, to treat nerve disorders and food poisoning (fish and meat)
Fruit sap is used to cleanse wounds and suppuration of boils
Crushed young leaves are applied to get rid of head lice
Ground flowers are applied for skin diseases

Scientific Research

Chemical constituents:

Annonaceous acetogenins: muricin H and I, muricoreacin, murisolin, murihexocin C, annonacin, annonacinone, annomontacin, cis-annomontacin, cis-corossolone, xylomaticin, annocatalin, solamin, annomuricin A from seeds, leaves and dried pericarp

Bioactivity :

Ethyl acetate extract of pericarp: antileishmanial activity; aqueous extract of leaves: protects and preserves pancreatic β-cell integrity; muricoreacin and murihexocin C: antitumour activity against pancreatic and colon carcinoma; ethanol extract of stem bark: inhibits cytopathic effect of Herpes simplex virus

Clinical:

Note :

Ripe fruits are edible

Caution : Seeds are poisonous

References :

Adewole, S. O. and Martins, E. A. C., (2006), Morphological Changes and Hypoglycemic Effects of Annona Muricata Linn. (Annonaceae) Leaf Aqueous Extract on Pancreatic Β-Cells of Streptozotocin-Treated Diabetic Rats, African Journal of Biomedical Research, 9, 173-187.

Jaramilloa, M. C. et al., (2000), Cytotoxicity and antileishmanial activity of Annona muricata pericarp, Fitoterapia, 71(2), 183-186.

Kim, J. S. et al., Muricoreacin and murihexocin C, mono-tetrahydrofuran acetogenins from the leaves of Annona muricata in honour of professor G. H. Neil Towers 75th birthday, Phytochemistry, 49(2), 565-571.

Liaw, C. C. et al., (2002), New Cytotoxic Monotetrahydrofuran Annona- ceous Acetogenins from Annona muricata, Journal of Natural products, 65(4), 470-475.

Padma, P. et al., (1998), Effect of the extract of Annona muricata and Petunia nyctaginiflora on Herpes simplex virus, Journal of Ethnopharma- cology, 61(1), 81-83.

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