Artocarpus heterophyllus Lam.

Moraceae

Synonym:

Artocarpus integrifolia sensu Trimen

Common Names:
Kos (S)
Palakkai, Palasu (T)
Jak (E)
Panasa (Sa)

Traditional Knowledge

Useful plant parts :
Leaf, root, fruit, seed and latex

Uses in traditional medicine :

  •  Latex of the young shoots is applied on swellings
  • Salad prepared with very young leaves and red onion is taken  for gastric ulcers
  • Herbal tea prepared with mature leaves is taken to reduce blood glucose levels
  • Leaves are used to treat insomnia and urinary calculi in bladder
  • Roots are antiasthmatic and used to treat skin diseases

Scientific Research

Chemical constituents:

Protein: jacalin, prenylflavones: artocarpine, artocarpetin, artocarpetin A, cycloheterophyllins, artonins A and B from plant and artocarpanone from wood; phenolics: artocarpesin, norartocarpetin and oxyresveratrol from fruit and heterophylol from roots; chalcones: artocarpusins A–C, artocarmitins A–C, artocarmins A–D, arylbenzofuran derivative: artocarstilene A from twigs and wood

 

Bioactivity :

Methanol extract of root bark and fruits: antibacterial; artocarpesin: anti-inflammatory; methanol extract of seeds: cytotoxic; jacalin: can be used for tumour detection; artocarpanone: skinwhitening agent, antioxidative; ethanol extract of leaves: hypoglycaemic, hypolipidaemic

 

Clinical:

Hot water extract of leaves shows improved glucose tolerance in healthy adults and diabetic patients

 

References :

Arung, E. T. et al., (2006), Inhibitory Effect of Artocarpanone from Artocarpus heterophyllus on Melanin Biosynthesis, Biological and Pharmaceutical Bulletin, 29(9), 1966-1969.

Di, X. et al., (2013), New phenolic compounds from the twigs of Artocarpus heterophyllus, Drug Discov Ther, 7(1), 24-8.

Fang, S. C. et al., (2008), Anti-inflammatory Effects of Phenolic Compounds Isolated from the Fruits of Artocarpus heterophyllus, Journal of Agricultural and Food Chemistry, 56, 4463-4468.

Feng, N. K. et al., (1998), Scavenger and antioxidant properties of prenylflavones isolated from Artocarpus heterophyllus, Free Radical Biology & Medicine, 25(2), 160-168.

Fernando, M. R. et al., (1991), Effect of Artocarpus hetero p~phyl~ us and Asteracanthus loivgifolia on glucose tolerance in normal human subjects and in maturity-onset diabetic patients, Journal of Ethnophurma- cology, 31, 277-282.

Kabir, S., (1998), Jacalin: a jackfruit (Artocarpusheterophyllus) seed-derived lectin of versatile applications in immunobiological research, Journal of Immunological Methods, 212(2), 193-211.

Khan, M. R. et al., (2003), Antibacterial activity of Artocarpus heterophyl- lus, Fitoterapia, 74, 501-505.

Lin, C. N. et al., (1995), Flavonoids from Artocarpus heterophyllus, Phytochemistry, 39(6), 1447-1451.

Nguyen, N. T. et al., (2012), Tyrosinase Inhibitors from the Wood of Artocarpus heterophyllus, J Nat Prod.

Omar, H. S. et al, (2011), Antioxidant activity of Artocarpus heterophyl- lus Lam. (Jack Fruit) leaf extracts: remarkable attenuations of hyperglyce- mia in streptozotocindiabetic rats, scientific world journal, 11, 788-800.

Patel, R. M. and Patel, S. K., (2011), Cytotoxic activity of methanolic extract of Artocarpus heterophyllus against A549, Hela and MCF-7 cell lines, Journal of Applied Pharmaceutical Science, 1(7), 167-171.

Wei, B. L. et al., (2005), Antiinflammatory Flavonoids from Artocarpus heterophyllus and Artocarpus communis, Journal of Agricultural and Food Chemistry, 53, 3867-3871.

Copyrights Reserved By
Natures Beauty Creations

Share

Copy Protected by Chetan's WP-Copyprotect.