Azadirachta indica A. Juss
Traditional Knowledge
Useful plant parts :
Leaf, seed, gum and root
Uses in traditional medicine :
- Seed oil is applied on chronic skin diseases
- Decoction of the leaves is used to wash ulcers
- Fresh young leaf juice is taken to get rid of intestinal worms
- Leaves are used as an antiseptic in treating chickenpox
- Gum is used to treat jaundice, skin diseases and catarrh
- Root is used to treat typhoid fever
Scientific Research
Chemical constituents:
Tetranortriterpenes: meliacinolin, nimbin, nimbidin, gedunin, diterpenes: sugiol, nimbiol, limonoids: margosinolide, isomargosinolide, azadiradione, limocin E, nimolicinol, azadirachtin, vepaol from leaves, twigs, bark and seeds; substituted aromatic ester: nimbocetin from fruits; flavonoids: quercetin, kaempferol and their derivatives from leaves
Bioactivity :
Alcohol extract of leaves: anti-inflammatory, peripheral analgesic, antipyretic, antimicrobial, hepatoprotective; leaf extract and seed oil: hypoglycaemic; gedunin: antimalarial; seed oil: active against dental plaque forming microbes; meliacinolin: α-glucosidase and α-amylase inhibitor; some limohoids: anticancer
Clinical:
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