Celastrus paniculatus Willd.
Traditional Knowledge
Useful plant parts :
Seed and oil
Uses in traditional medicine :
- A drop of oil extracted from seeds is placed on the tongues of children as a brain tonic
Scientific Research
Chemical constituents:
Sesquiterpene polyol esters: dihydroxy agrofuran derivatives and angulatueoid from seed oil and seed extracts
Bioactivity :
Seed oil: decrease the turnover of central monoamines and involves in aminergic systems in the learning and memory process; aqueous and methanol extracts of seeds: cognitive enhancing properties, hypolipidaemic; methanol extract of flowers and whole plant: analgaesic, anti-inflammatory
Clinical:
Ingredient of the tablet ‘Geriforte’ which can be used for menopausal symptoms; Ingredient of the syrup, ‘Mentat’ used for treatments of hyperkinetic children
References : Ahmad, F. et al (1994), Preliminary screening of methanolic extracts of Celastrus paniculatus and Tecomella undulata for analgesic and anti-inflammatory activities, Journal of Ethnopharmacology, 42(3), 193-198. Borbone, N. et al.,(2007), Identification of a new sesquiterpene polyol ester from Celastrus paniculatus, Planta Med, 73(8), 792-4. Borrelli, F., (2004), New Sesquiterpenes with Intestinal Relaxant Effect from Celastrus paniculatus, Planta Med, 70(7), 652-656. Kumar, M. H. V. and Gupta, Y. K., (2002), Antioxidant property of Celastrus paniculatus Willd.: a possible mechanism in enhancing cognition, Phytomedicine, 9(4), 302-311. Nalini, C. et al., (1995), Effects of Celastrus paniculatus on passive avoidance performance and biogenic amine turnover in albino rats, Journal of Ethnopharmacology, 47(2), 101-108. Patil, R. H. et al., (2010), Hypolipidemic Effect of Celastrus paniculatus in Experimentally Induced Hypercholesterolemic Wistar Rats, Indian J Clin Biochem, 25(4), 405-10. Saxena, S. C., (1978), Use of Geriforte in the Menopausal Syndrome (A Preliminary Study), Probe, 1, 20-27. Shah, L.P., (1992), An open clinical trial of Mentat in hyperkinetic children, Probe, 2, 125-129.
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