Clerodendrum infortunatum L.
Traditional Knowledge
Useful plant parts :
Leaf and root
Uses in traditional medicine :
- Ground roots are applied on tumour
- Leaf juice mixed with gingerly seed oil is used topically to treat chronic skin diseases
Scientific Research
Chemical constituents:
Phenolics, flavonoids, saponins, sterols: 24β-ethylsterols, clerosterol, 22-dehydroclerosterol, terpenes: cterodinin A, oleanolic acid from plant
Bioactivity :
Ethanol extract of leaves: free radical scavenger, wound healing, hepatoprotective; saponins: analgaesic and anticonvulsant; methanol extract of plant: anticancer
Clinical:
References : Akihisa, T. et al., (1989), Sterols of some Clerodendrum species (Verbenaceae): occurrence of the 24 alpha- and 24 beta-epimers of 24-ethylsterols lacking a delta 25-bond, Steroids, 53(3-5), 625-38. Gouthamchandra, K. et al., (2010), Free radical scavenging, antioxidant enzymes and wound healing activities of leaves extracts from Cleroden- drum infortunatum L., Environmental Toxicology and Pharmacology, 30, 11-18. Pal, D. et al., (2009), Analgesic and anticonvulsant effects of saponin isolated from the leaves of Clerodendrum infortunatum Linn. in mice, Indian journal of experimental biology, 47, 743-747. Sannigrahi, S. et al, (2012), Terpenoids of methanol extract of Cleroden- drum infortunatum exhibit anticancer activity against Ehrlich’s ascites carcinoma (EAC) in mice, Pharm Biol, 50(3), 304-9.
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