Couroupita guianensis Aubl.
Traditional Knowledge
Useful plant parts :
Leaf
Uses in traditional medicine :
- Leaves are used to treat skin diseases
Scientific Research
Chemical constituents:
Alkaloids, steroids, triterpenoids, tannins, glycosides, flavonoids and phenols such as 4-hydroxybenzoic acid from leaves; indole derived compounds: tryptanthrin, indigo, indirubin, isatin, isatoic anhydride and citric, malic and isocitric acid found in fruit; terpenes: eugenol, linalool, (E,E)-farnesol and nerol from flowers
Bioactivity :
Ethanol extract of whole plant: antibacterial, wound healing, stimulates human skin fibroblast proliteration; ethanol extract of leaves: antinociceptive, anti-inflammatory; methanol extract of flowers: stimulates cell mediated and antibody mediated immune responses; isatin: antioxidative, anticancer; chloroform extract of fruit: antimicrobial, antibiofilm forming
Clinical:
Note :
Introduced species to Sri Lanka, Origin – South America
References : Al-Dhabi, N. A. et al., (2012), Antimicrobial, antimycobacterial and antibiofilm properties of Couroupita guianensis Aubl. fruit extract, BMC Complement Altern Med, 12, 242. Bergman, J. et al., (1985), The structure and properties of some indolic constituents in Couroupita guianensis Aubl., Tetrahedron, 41(14), 2879-2881. Linga, R. M. et al., (2011), Screening of traditional medicinal plants for secondary metabolites, International Journal of Research in Pharmaceuti- cal Sciences, 2(4), 643-647. Khan, M. R. et al., (2003), Antibiotic Activity of Couroupita guianensis , Journal of Herbs, Spices & Medicinal Plants, 10(3), 95-108. Martínez, A. et al., (2011), Protective effect against oxygen reactive species and skin fibroblast stimulation of Couroupita guianensis leaf extracts, Natural Product Research, 21, 44. Nelson, E. K. and Wheeler, D. H., (1937), Some Constituents of the Cannonball Fruit (Couroupita Guianensis, Aubl.), Journal of the American Chemical Society, 59(12), 2499-2500. Pinheiro, M. M. et al., (2013), Anti-inflammatory activity of ethanol extract and fractions from Couroupita guianensis Aublet leaves, J Ethnopharmacol, 146(1), 324-30. Pradhan, D. et al., (2009), Evaluation of the immunomodulatory activity of the methanolic extract of Couroupita guianensis Aubl. flowers in rats, Indian Journal of Natural Products and Resources, 8(1), 37-42. Pradhan, D. et al., (2009), Evaluation of the immunomodulatory activity of the methanolic extract of Couroupita guianensis Aubl. Flowers in rats, Natural product radiance, 8(1), 37-42. Premanathan, M. et al., (2012), Antioxidant & anticancer activities of isatin (1H-indole-2,3-dione), isolated from the flowers of Couroupita guianensis Aubl, Indian J Med Res, 136(5), 822-6. Pinheiro, M. M. G. et al., (2010), Antinociceptive activity of fractions from Couroupita guianensis Aubl. Leaves, Journal of Ethnopharmacol- ogy, 127, 407-413. Umachigi, S. P. et al., (2007), Antimicrobial, Wound Healing and Antioxidant potential of Couroupita guianensis in rats, Pharmacologyon- line, 3, 269-281. Wong, K. C. and Tie, D. Y., (1995), Volatile Constituents of Couroupita guianensis Aubl. Flowers, Journal of Essential Oil Research, 7(2), 225-227.
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