Justicia adhatoda L.
Traditional Knowledge
Useful plant parts :
Whole plant, leaf, root, flower, bark and fruit
Uses in traditional medicine :
- Expressed leaf juice is given for diarrhoea, dysentery, cough, asthma and other bronchial diseases
- Used as remedy to stop internal and external bleedings such as bleeding gums, piles and peptic ulcers
- An ingredient in decoctions for all types of fever due to kapha and pitta doshas
- An expectorant, antispasmodic and blood purifier
Scientific Research
Chemical constituents:
Alkaloids: palmatine, vasicinone, vasicinolone, berberine, vasicine, adhatodine and anisotine from roots and leaves
Bioactivity :
Aqueous and alcohol extracts of leaves: antibacterial, anti-quorum sensing, chemopreventive; methanol extract of plant: acetylcholinesterase inhibitor, some of the reported alkaloids are anti-inflammatory
Clinical:
Herbal oral solution form ulated with other plants is effective in non-complicated acute respiratory tract infections; Herbal toothpaste formulated with other plants is effective for oral hygiene and gingival health
References : Ali, S. k. et al., (2013), In-vitro evaluation of selected Egyptian traditional herbal medicines for treatment of alzheimer disease, BMC Complement Altern Med, 13(1). Gulfraz, M. et al., (2004), Investigation for Bioactive Compounds of Berberis Lyceum Royle and Justicia Adhatoda L., Ethnobotanical Leaflets, 1, 5. Jha, D. K. et al., (2012), Detection and confirmation of alkaloids in leaves of Justicia adhatoda and bioinformatics approach to elicit its anti-tuberculosis activity, Appl Biochem Biotechnol, 168(5), 980-90. Narimanian, M. et al., (2005), Randomized trial of a fixed combination (KanJang) of herbal extracts containing Adhatoda vasica, Echinacea purpurea and Eleutherococcus senticosus in patients with upper respiratory tract infections, Phytomedicine, 12(8), 539-47. Shinwari, Z. K. et al., (2009), Assessment of antibacterial activity of three plants used in Pakistan to cure respiratory diseases, African Journal of Biotechnology, 8(24), 7082-7086. Singh, B. and Sharma, R. A., (2013), Anti-inflammatory and antimicro- bial properties of pyrroloquinazoline alkaloids from Adhatoda vasica Nees, Phytomedicine, 20(5), 441-5. Singh, R. P. et al., (2000), Modulatory influence of Adhatoda vesica (Justicia adhatoda) leaf extract on the enzymes of xenobiotic metabo- lism, antioxidant status and lipid peroxidation in mice, Biomedical And Life Sciences, 213(1-2), 99-109. Zaki, A. A. et al., (2013), Assessment of anti-quorum sensing activity for some ornamental and medicinal plants native to egypt, Sci Pharm, 81(1), 251-8.
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