Nauclea orientalis (L.) L.

Rubiaceae

Common Names:
Bakmi (S)
Attuvangi, Vammi (T)
Yellow cheesewood (E)
Bhantriya (Sa)

Traditional Knowledge

Useful plant parts :
Leaf and fruit

Uses in traditional medicine :

Crushed young leaves are applied on boils in the skin
Ripe fruits are taken for gastric ulcers
Act as an antipyretic, vulnerary and an antidiarrhoeic
Used to treat tumours and toothache

Scientific Research

Chemical constituents:

Alkaloids: naucleaorals A and B, strictosidine lactam, nauclealines A and B, naucleosides A and B, terpene glucosides: naucleaorine, epimethoxynaucleaorine, terpenes: ursoic acid and its esters, oleanolic acid, alkaloid glycosides: strictosamide, vincosamide, pumiloside from root, stem and bark

Bioactivity :

Ethanol extract of leaves: antioxidative, anthelmintic; naucleaoral A: cytotoxic to human cervical carcinoma cell lines; naucleaorine and epimethoxynaucleaorine: antimalarial

Clinical:

References :

Hea, Z. D. et al., (2005), Antimalarial Constituents from Nauclea orientalis (L.) L., Chemistry & Biodiversity, 2, 1378-1386.

Raghavamma, S. T. V. et al., (2011), In vitro antioxidant potential of crude extract from leaves of Nauclea orientalis Linn., Journal of Pharmacy Research, 4(5), 1548-1549.

Raghavamma, S. T. and Rao, N. R., (2010), In vitro Evaluation of Anthelmintic Activity of Nauclea orientalis Leaves, Indian J Pharm Sci, 72(4), 520-1.

Sichaem, J. et al., (2010), Two new cytotoxic isomeric indole alkaloids from the roots of Nauclea orientalis, Fitoterapia, 81, 830–833.

Zhang, Z. et al., New indole alkaloids from the bark of Nauclea orientalis, J Nat Prod, 64(8), 1001-5.

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