Ruta graveolens L.

Rutaceae

Common Names:
Aruda (S)
Aruthampachchai, Aruvadam (T)
Garden Rue (E)
Guchhapatra (Sa)

Traditional Knowledge

Useful plant parts :
Leaf

Uses in traditional medicine :

  • Herbal oil prepared with fresh leaf and pure coconut oil is applied for headaches caused by coughs and colds in children

Scientific Research

Chemical constituents:

Alkaloids: kokusaginine and skimmianine, coumarins: rutamarin, bergapten, isopimpinellin, xanthatoxin and umbelliferone from plant

Bioactivity :

Alcoholic extract of plant: anti-inflammatory, antibacterial, sedative, antifertility activity in females, cytotoxic to cancer cells

 

Clinical:

References :

Steck, W. et al., (1971), Coumarins and alkaloids from cell cultures of Ruta graveolens, Phytochemistry, 10(1), 191–194.

Raghav, S. K. et al., (2006), Anti-inflammatory effect of Ruta graveolens L. in murine macrophage cells, Journal of Ethnopharmacology, 104(2), 234–239.

Ivanova, A. et al., (2005), Antimicrobial and cytotoxic activity of Ruta graveolens, Fitoterapia, 76(3–4), 344–347.

Milesi, S. et al., (2001), Ruta graveolens L.: a promising species for the production of furanocoumarins, Plant Science, 161(1), 189–199.

Gandhi, M. et al., (1991), Post-coital antifertility activity of Ruta graveolens infemale rats and hamsters, Journal of Ethnopharmacology, 34(1), 49–59.

Mohomad, A. O. et al., (2010),Antihyperglycemic, antihyperlipidemic and antioxidant effects and the probable mechanisms of action of Ruta graveolens infusion and rutin in nicotinamide-streptozotocin-induced diabetic rats, Diabetologia Croatica, 39(1), 15-35.

Ratheesh, M. and Helen, A., (2007), Anti-inflammatory activity of Ruta graveolens Linn on carrageenan induced paw edema in wistar male rats, African journal of biotechnology, 6(10), 1209-1211.

Preethi, K. C. et al., (2006), Anti-tumor activity of Ruta graveolens extract, Asian pacific journal of cancer prevention, 7, 439- 443.

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