Strychnos nux-vomica L.

Loganiaceae

Common Names:
Goda-kaduru (S)
Eddi, Etti (T)
Nux-vomica (E)
Vishamushti (Sa)

Traditional Knowledge

Useful plant parts :
Young shoot and leaf

Uses in traditional medicine :

  • Young shoots with fresh leaves are ground into a paste and applied on wounds and ulcers

Scientific Research

Chemical constituents:

Indole alkaloids: strychnine, isostrychnine, protostrychnine, n-oxystrychnine, pseudostrychnine, brucine, brucine N-oxide, vomicine, strychnochrysine,  strynuxlines A and B, hydroxycinnamic acid ester: chlorogenic acid, iridoid glucosides: loganic acid and its derivatives from seeds and roots

Bioactivity :

Alkaloids from seeds: anticancer; brucine and brucine-N-oxide: anti-inflammatory, antinociceptive; alcohol and aqueous extract of seeds: antihyperglycaemic

 

Clinical:

Note :

A poisonous plant in Sri Lanka

References :

Biala, R. G. et al., (1998), Strychnochrysine, a New Bisindole Alkaloid from the Roots of Strychnos nux-vomica, Journal of Natural Products, 61(1), 139–141.

Bhati, R. et al., (2012), Strychnos nux-vomica seeds: Pharmacognostical standardization, extraction, and antidiabetic activity, J Ayurveda Integr Med, 3(2), 80-4.

Deng, X. K. et al., (2006), The anti-tumor effects of alkaloids from the seeds of Strychnos nux-vomica on HepG2 cells and its possible mechanism, Journal of Ethnopharmacology, 106(2), 179–186.

Fu, Y. et al., (2012), Strynuxlines A and B, Alkaloids with an Unprec- edented Carbon Skeleton from Strychnos nux-vomica, J Nat Prod.

Yin, W. et al., (2003), Analgesic and anti-inflammatory properties of brucine and brucine N-oxide extracted from seeds of Strychnos nux-vomica, Journal of Ethnopharmacology, 88(2-3), 205-214.

Zhang, X. et al., (2003), Iridoid glucosides from Strychnosnux-vomica: Reports on Structure Elucidation, Phytochemistry, 64(8), 1341–1344.

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