Strychnos potatorum L.f.
Traditional Knowledge
Useful plant parts :
Seed
Uses in traditional medicine :
- Seeds soaked over night in water are ground and applied around the eyes for eye diseaes
Scientific Research
Chemical constituents:
Alkaloids: diaboline and its derivativs, cantleyine, 18,19-dihydrousambarensine, polyneuridine, norharmane, akuammidine, nor-C-flurorocurarine, ochrolifuanine A and E, bisnordihydrotoxiferine, normacusine B, normavacurine, henningsamine, 11-methoxyhenningsamine, dihydrolongicaudatine, dihydrolongicaudatine Y, antirhine, desacetylretuline and β-sitosterol, stigmasterol, terpenes: oleanolic acid and its derivatives from seeds and root bark; polysaccharides: galactomannan and galactan containing coagulant from polysaccharide fraction of seeds
Bioactivity :
Methanol extract of seed: hypernatraemic, hyperchloremic, hyperkalaemic, diuretic, antianaphylactic, antidiarrhoeal; aqueous extract of seeds: hepatoprotective; seed powder and aqueous seed extract: antiulcer, antiarthritic
Clinical:
References : Adinolfi, M. et al., (1994), Composition of the coagulant polysaccharide fraction from Strychnos potatorum seeds, Carbohydrate Research, 263(1), 103–110. Biswas, S. et al., (2001), Study on the diuretic activity of Strychnos potatorum Linn. seed extract in albino rats, Phytomedicine, 8(6), 469–47. Biswas, S. et al., (2002), Antidiarrhoeal activity of Strychnos potatorum seed extract in rats, Fitoterapia, 73, 43-47. Ekambaram, S. et al., (2010), Evaluation of antiarthritic activity of Strychnos potatorum Linn seeds in Freund’s adjuvant induced arthritic rat model, BMC Complement Altern Med, 10, 56. Massiot, G. et al., (1992), Alkaloids from roots of Strychnos potatorum, The International Journal of Plant Biochemistry, Phytochemistry, 31(8), 2873–2876. Patil, U. J. et al., (2011), Antianaphylactic and mast cell stabilization activity of Strychnos potatorum Linn. Seed, Pharmacognosy Res, 3(3), 208-13. Sanmugapriya, E. and Venkataraman, S., (2006), Studies on hepatopro- tective and antioxidant actions of Strychnos potatorum Linn. seeds on CCl4-induced acute hepaticinjury in experimental rats, Journal of Ethnopharmacology, 105, 154–160. Sanmugapriya, E. and Venkataraman, S., (2007), Antiulcerogenic potential of Strychnos potatorum Linn seeds on Aspirin plus pyloric ligation-induced ulcers in experimental rats, Phytomedicine, 14, 360–365. Singh, H. et al., (1975), Diaboline from Strychnos potatorum, Phytochemistry, 14, 587-588.
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