Cycas nathorstii J. Schust.

Cycadaceae

Common Names:
Madu (S)
Madanagama, Maduppanai (T)
Cycus (E)
Varaguna (Sa)

Traditional Knowledge

Useful plant parts :
Tender leaf and seed

Uses in traditional medicine :

  • Food prepared from powdered seeds is taken to reduce haemorrhoids
  • Tender leaves are prepared as a vegetable for bleeding piles
  • Powdered roasted seeds are mixed with coconut oil and applied to wounds, boils and other skin diseases
  • Juice of tender leaves is taken for flatulence and vomiting

Scientific Research

Chemical constituents:

Amino acids: α-amino-β-methylaminopropionic acid and non-protein amino acids: hexylalanine derivative, leucine, betaine, cycasin from seeds; sterol-β-D-glucosides from seed flour; bioflavonoid: mentoflavone derivative from leaf

Bioactivity :

Acetone extract of plant: antibacterial; sterol β-D-glucosides and α-amino-β-methylamino propionic acid: potential neurotoxins

 

 

Clinical:

References :

Khabazian, I. et al., (2002), Isolation of various forms of sterol β-d-glucoside from the seed of Cycas circinalis: neurotoxicity and implications for ALS-parkinsonism dementia complex, Journal of Neurochemistry, 82(3), 516-528.

Laqueur, G. L. and Spatz, M., (1968), Toxicology of cycasin, Cancer research, 28, 2262-2267.

Leach, A. J. et al., (1988), Antibacterial activity of some medicinal plants of Papua New Guinea, Science in New Guinea, 14(1), 1-7.

Li, C. J. et al., (1996), Nonprotein amino acids from seeds of Cycas circinalis and Phaseolus vulgaris, Phytochemistry, 42(2), 443-445.

Moawad, A. et al., (2010), Phytochemical investigation of Cycas circinalis and Cycas revoluta leaflets: moderately active antibacterial biflavonoids, Planta Med, 76(8), 796-802.

Vega, A. and Bell, E. A., α-Amino-β-methylaminopropionic acid, a new amino acid from seeds of Cycas circinalis, Phytochemistry, 6(5), 759-762.

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